The Mark of Cain

One of those phrases that gets misused. Here's Jeffrey A White:

So, too, the "mark of Cain" of Gen. 4.15, which is an emblem of the Lord's protection and guidance, and not a sign of ostracism (that has been effected already), an indication that Cain is sacer, the god's for good or ill.

Might the Cainish 'Mark of the Beast' be something similar?